Other Conditions & Exposures

Expert reports about Other Conditions & Exposures


THE SAFETY OF ENZYME REPLACEMENT THERAPY FOR TREATMENT OF GAUCHER DISEASE DURING PREGNANCY OR BREASTFEEDING

 

THIS MEDICATION CAN CAUSE HARM TO YOUR BABY:

There is limited evidence available on the safety of enzyme replacement therapy during pregnancy. These medications should not be used during pregnancy unless the benefits of treatment outweigh potential risks, as determined by your doctor.

 

What is enzyme replacement therapy?

Enzyme replacement therapy provides your body with synthetic enzymes to replace an enzyme that is not present in normal amounts in people with Gaucher disease. There are 3 different types of enzyme replacement therapy medications available, including imiglucerase (Cerezyme), velaglucerase alfa (VPRIV), and taliglucerase alfa (Elelyso). These medications are given intravenously in your doctor’s office or at an outpatient clinic. The infusion usually takes about 1 to 2 hours and is given every 2 weeks. These medications are only available by prescription from your doctor.


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